2026

Wang et al., 2026, Bilaterian AMPA Receptors, J Gen Physiol, iGluR alignment - manually trimmed

Wang et al., 2026, Bilaterian AMPA Receptors, J Gen Physiol, iGluR tree - manually trimmed alignment

Wang et al., 2026, Bilaterian AMPA Receptors, J Gen Physiol, iGluR alignment - untrimmed

Wang et al., 2026, Bilaterian AMPA Receptors, J Gen Physiol, iGluR tree - untrimmed alignment

Wang et al., 2026, Bilaterian AMPA Receptors, J Gen Physiol, TARP alignment - manually trimmed

Wang et al., 2026, Bilaterian AMPA Receptors, J Gen Physiol, TARP tree - manually trimmed alignment

Wang et al., 2025, Bilaterian AMPA Receptors, J Gen Physiol, TARP alignment - untrimmed

Wang et al., 2026, BIlaterian AMPA Receptors, J Gen Physiol, TARP tree - untrimmed alignment

Trimmed amino acid sequence alignment (FASTA format, 672 amino acid positions)
of 388 bilaterian, cnidarian, and outgroup iGluR sequences.

Maximum likelihood tree based on above iGluR trimmed alignment.

Untrimmed amino acid sequence alignment (FASTA format, 6688 amino acid positions)
of 388 bilaterian, cnidarian, and outgroup iGluR sequences.

Maximum likelihood tree based on above iGluR untrimmed alignment

Trimmed amino acid sequence alignment (FASTA format, 181 amino acid positions)
of 65 TARP-like sequences.

Maximum likelihood tree based on above TARP trimmed alignment

Untrimmed amino acid sequence alignment (FASTA format, 1056 amino acid positions of
65 TARP-like sequences.

Maximum likelihood tree based on above untrimmed TARP alignment.

Wang et al., 2026, Determinants of Ligand Selectivity, Alignment

Wang et al., 2026, Determinants of Ligand Selectivity, Tree

Wang 2026, Determinants of Ligand Selectivity, Tree with support values

Amino acid sequence alignment (FASTA format) of 458 animal iGluR sequences and two plant GLR sequences. From “Molecular determinants of ligand selectivity in diverse ionotropic glutamate receptors” by Wang et al.

FastTree (Newick format) of 458 animal iGluR sequences and two plant GLR sequences. From “Molecular determinants of ligand selectivity in diverse ionotropic glutamate receptors” by Wang et al. First file without support values; second file with SH-aLRT and Ultrafast Bootstrap branch support values.

2023

iGluR alignment - hydrophobic substitutions

iGluR tree - hydrophobic substitutions

Amino acid sequence alignment (FASTA format) of 203 animal iGluR sequences and one plant iGluR sequence. From “Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain” by Sintsova et al.

FastTree (Newick format) of 203 animal iGluR sequences and one plant iGluR sequence. From “Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain” by Sintsova et al.

ASICs Dataset S1

Alignment of 700 DEG/ENaC sequences. From “Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution” by Martí-Solans et al. FASTA format.

2022

FaNaC MAFFT Alignment

Alignment of 544 DEG/ENaC sequences. From “Molecular determinants of neuropeptide sensitivity in the FMRFamide-gated sodium channel family” by Dandamudi et al. FASTA format.